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2025 Research Contest

2025 Research Contest

Cover Art for the Scientific Ballooning Handbook - 50th Anniversary Edition

Submit custom artwork for the new scientific ballooning handbookChallenge type: Creative (multimedia & design)Agency name: National Aeronautics and Space Administration - Science Mission DirectorateTotal cash prizes: $0.00 ...


Drug Repurposing and Repositioning Insights for Treating SUDs Challenge

Uncovering novel therapeutic approaches for rapid translation to clinical practiceChallenge type: IdeasAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $10,000,000.00 ...


xTechLive Pitch Competition

The U.S. Army xTech Program live pitch competition at the 2025 Consumer Electronics Show!The U.S. Army invites interested entities to participate in the U.S. Army xTech Live pitch competition, designed for eligible small to medium businesses attending the Consumer Electronics Show (CES).Challenge type: Technology demonstration and hardwareAgency name: Department of Defense - ArmyTotal cash prizes: $10,000,000.00 ...


Dual Horizons: U.S.-India Satellite Tracking Challenge

Identify technology to detect and track satellites in LEO in contested environments.Identify technologies to detect and track satellites in low earth orbit (LEO) in contested environments for up to $150,000 in awards.Challenge type: Analytics, visualizations, algorithmsAgency name: Department of DefenseTotal cash prizes: $15,000,000.00 ...


Targeted Genome Editor Delivery (TARGETED) Challenge

Revolutionizing technology development of delivery systems for in vivo genome editing.A $6,000,000 competition to improve in vivo delivery technologies for genome editors in two Target Areas: 1. Programmable delivery systems, and 2. Non-viral delivery across the blood-brain barrier.Challenge type: ScientificAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $600,000,000.00 ...


First Responder UAS Wireless Data Gatherer Challenge

NIST competition seeks innovative technologies and researchers for UAS 6.0 Challenge. Join us for the sixth prize challenge in our Uncrewed Aircraft Systems (UAS) competition series: The First Responder UAS Wireless Data Gatherer Challenge (UAS 6.0)!Challenge type: Technology demonstration and hardwareAgency name: Department of Commerce - National Institute of Standards and TechnologyTotal cash prizes: $73,000,000.00 ...


Barriers and Solutions to Building Community Partnerships in Deploying Remote Assessments

Creating actionable steps to reduce barriers between researchers and communitiesChallenge type: IdeasAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $30,000,000.00 ...


Remote Assessments of Substance Use Disorder (SUD)-Relevant Measurements

Highlighting current best practices and state-of-the-art approaches in remote monitoringChallenge type: Technology demonstration and hardwareAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $30,000,000.00 ...


The Choova Njinga Innovation Challenge

Pedaling for Innovation, One Ride at a TimeThe Choova Njinga Innovation Challenge seeks to foster transformative and scalable bicycle-based solutions to improve rural Malawi and Zambia livelihoods. Challenge type: IdeasAgency name: U.S. Agency for International DevelopmentTotal cash prizes: $220,000,000.00 ...


U.S.-Japan Global Innovation Challenge

Identify technologies that can help advance biodefense solutions & counter disinformation.Identify novel technologies that can help advance biodefense solutions and counter disinformation.Challenge type: Software and appsAgency name: Department of DefenseTotal cash prizes: $30,000,000.00 ...


South Pole Safety: Designing the NASA Lunar Rescue System

Create a system for astronaut rescue on the lunar surfaceCreate a compact, efficient system for astronaut rescue on the lunar surfaceChallenge type: IdeasAgency name: National Aeronautics and Space Administration Total cash prizes: $4,500,000.00 ...


xTech AI Grand Challenge

A competition to engage with DoD on the latest AI data processing effortsxTech is seeking cutting-edge technology solutions focused on the importance of preparing data for AI applications and the tools and techniques available to automate and streamline the processChallenge type: Software and appsAgency name: Department of Defense - ArmyTotal cash prizes: $200,000,000.00 ...


NEI Expand OHDSI Initiative for Eye Care and Ocular Imaging Challenge

Submit your innovative ideas related to eye care and vision research for leveraging OHDSI.This challenge seeks to expand the OHDSI network for vision research by incentivizing innovative ideas for leveraging real-world evidence. Prizes can support winner's integration into the network.Challenge type: ScientificAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $100,000,000.00 ...


Good Jobs in Clean Energy Prize

Building Partnerships for Good Jobs in Clean EnergyThis prize is designed to encourage coalition-building in communities across the country that focus on creating quality jobs and fostering an equitable and inclusive workforce in clean energy sectors.Challenge type: Business plansAgency name: Department of Energy Total cash prizes: $337,500,000.00 ...


2025 Growth Accelerator Fund Competition

Funding entrepreneur support organizations, to drive growth and innovation across America.Driving growth and innovation in entrepreneur support organizations to enhance support for small businesses in undercapitalized regions, industries, and communities across America.Challenge type: IdeasAgency name: Small Business AdministrationTotal cash prizes: $900,000,000.00 ...


EnergyTech University Prize 2025

Student and faculty competition with prizes available for energy tech elevationPrizes available to students who create/present an energy tech business plan & faculty who elevate energy entrepreneurship at their institutionChallenge type: Business plansAgency name: Department of Energy Total cash prizes: $54,500,000.00 ...


Gateways to Blue Skies Competition

Collegiate students tackling environmentally and socially conscious aviation solutions.The 2025 competition challenges collegiate students to conceptualize aviation systems that can be applied by 2035 or sooner to address challenges in agriculture.Challenge type: Business plansAgency name: National Aeronautics and Space Administration Total cash prizes: $6,400,000.00 ...


NIH Quantum Computing Challenge

Solve translational biomedical problems with quantum computingInnovative design solutions for novel applications of existing quantum-enabled technologies to apply toward use cases within clinical, translational, and biomedical problem areas are soughtChallenge type: Technology demonstration and hardwareAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $130,000,000.00 ...


NASA's Revolutionary Aerospace Systems Concepts - Academic Linkage (RASC-AL) Competition)

RASC-AL fuels innovation for aerospace systems concepts, analogs, & technology prototypingThrough RASC-AL, teams and their faculty advisors will design innovative solutions with supporting original engineering and analysis in response to one of three themes.Challenge type: IdeasAgency name: National Aeronautics and Space Administration Total cash prizes: $10,400,000.00 ...


Quit & Thrive Challenge

Community-Derived Solutions to Reduce Menthol Cigarette SmokingSeeking community solutions to reduce menthol cigarette smoking among groups with high rates of use, including youth, LGBTQ populations, people with lower incomes, and racial and ethnic minorities.Challenge type: ScientificAgency name: Department of Health and Human Services - National Institutes of HealthTotal cash prizes: $90,000,000.00 ...



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